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ATP,100mM Solution

Adenosine 5-triphosphate, disodium salt

CAS: 987-65-5;51963-61-2

Molecular Formula: C10H14N5Na2O13P3

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ATP,100mM Solution - Names and Identifiers

Name Adenosine 5-triphosphate, disodium salt
Synonyms ATP
ATP-NA2
5-ATP-Na2
5-ATP Na2
ATP disodium salt
ATP,100mM Solution
Adenosine Triphosphate Disodium
Adenosine disodium triphosphate
adenosine disodium 5-triphosphate
Adenosine 5-triphosphate disodium
Adenosine Triphosphate Disdium salt
5-Adenosine triphosphatedisodium salt
Adenosine-5-triphosphate,disodium salt
Adenosine 5-triphosphate disodium salt
Adenosine-5-triphosphate disodium salt
Adenosine 5-triphosphate, disodium salt
5Adenosinetriphosphoric acid disodium salt
Adenosine-5-triphosphoric acid disodium salt
adenosine-5-triphosphate disodium sigma grade
Adenosine-5-triphosphate disodium salt hydrate
adenosine, 5-(tetrahydrogen triphosphate), monosodium salt
9H-purin-6-amine, 9-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]pentofuranosyl]-, monosodium salt, monohydrate
CAS 987-65-5
51963-61-2
EINECS 213-579-1
InChI InChI=1/C10H16N5O13P3.2Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/q;2*+1/t4-,6-,7-,10-;;/m1../s1

ATP,100mM Solution - Physico-chemical Properties

Molecular FormulaC10H14N5Na2O13P3
Molar Mass551.14
Melting Point188-190℃
Boling Point951.4°C at 760 mmHg
Flash Point529.2°C
Solubility Soluble in water, insoluble in ethanol
Vapor Presure0mmHg at 25°C
AppearanceWhite crystal
Storage Condition-20℃
SensitiveEasily absorbing moisture
MDLMFCD00080339
Physical and Chemical PropertiesProperties:
This product is white powder, soluble in water, insoluble in ethanol, this product's infrared absorption spectrum, and the control spectrum (Spectrum set 903 figure), this product water solution sodium salt flame reaction.

This product is used as an energy supplement, a therapeutic drug to improve liver function, and also as a Biochemical reagent.

UseAuxiliary enzyme drugs for progressive muscular atrophy, sequelae of cerebral hemorrhage, cardiac insufficiency, myocardial disease and hepatitis and other diseases

ATP,100mM Solution - Risk and Safety

Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.

ATP,100mM Solution - Reference

Reference
Show more
1. Chen Zhou, Hu Yang, an Tuqi, Lu Hao, Guo Xiaodong, You Juan, Xiong Shanbai. Effect of short-time micro-running water treatment on fish meat quality of pond grass carp [J]. Journal of Fisheries, 2020,44(07):1198-1210.
2. Wang Ying, Zhou Chunxia, Hong Pengzhi, etc. Effects of crushed ice on physicochemical properties of myofibrillar protein in tilapia during cold storage [J]. Science and Technology of food industry, 2013, 34(010):120-123.
3. Zhou Jiaojiao, Wu Xiaoyang, Chen Zhou, Xiong Shanbai. Rapid prediction of freshness of Coptis Rubus by near infrared spectroscopy [J]. Journal of Huazhong Agricultural University, 2019,38(04):120-126.
4. Tan Wenxi, Liu Jian, Shangguan Mengyuan, et al. Effect of atrazine on serum sex hormone levels in healthy female mice and its significance [J]. Journal of Jilin University (Medicine edition), 2013, 39(6).
5. Zhu Yahui, Cao, Wen, Hongzhang, Chaohua. Evaluation of flavor characteristics of dried scallop Chlamys farreri [J]. Food and Fermentation Industry, 2016, 42(012):183-188.
6. Hui, Zhou, Qin, Lu, Nan, Gao, Chen, and so on. Expression of recombinant human alkaline phosphatase and its regulation of TNF-α release from human leukocytes [J]. Journal of Northeast Agricultural University, 2020, v.51;No.301(03):56-63.
7. Wang Di, Wei Lan, Liu Xi, et al. Effects of anti-metabolic drugs on nucleotide metabolism in human tumor cells [J]. Northwest Journal of Pharmacy, 2015, 000(001):59-65.
8. Zhang Xiaokang Shangguan Super Chen Changbao Zhang Lili Zhou Jie Zhu Shuhua. Regulation of nitric oxide on energy metabolism of refrigerated peach fruit [J]. Preservation and processing 2019 19(04):1-9.
9. Zhang Miao, Jiang, Yu, Tang, et al. Effects of cold shock combined with Betaine treatment on chilling injury and energy metabolism of summer squash [J]. Food science 2020 v.41;No.620(07):193-199.
10. Li Yao Yao, Cao Mao Mao Mao, Wang Xiaolu, etc. Effects of exogenous p-coumaric acid treatment on phenylpropane metabolism and antioxidant capacity of postharvest peach fruit [J]. Food Science, 2019, 40(23).
11. Huang Shengdong Chen Song Pan Jiang ball Cai Ying Li Si Dong Li puwang Yang Xihong Wu Yuying. Effects of different molecular weight chitosan on preservation of tilapia fillets during cold storage [J]. Science and Technology of Food Industry, 2015, 36(19):318-321.
12. Wu Zhanxia, Pan Jiang ball, Yang Zi-Ming, Chen Song, Huang Shengdong, Li puwang, Yang Xihong, Li Si-dong. Effect of mixed molecular weight chitosan combined with ozone sterilization on preservation of tilapia fillets during cold storage [J]. Journal of Guangdong Ocean University, 2016,36(03):71-75.
13. Chen Shi-da, Guo Mei-Chen, Yang Liu-ming, et al. Effect of pretreatment on fresh-keeping quality of cultured pseudosciaena crocea [J]. Science and Technology of food industry, 2018(17):258-262.
14. Zhu Weihao, Zheng Zhu, Sun Kai, Yang Mengzi, Qian Maosheng, Mo Yaonan. Temporal changes of total adenylate and adenylate energy charge in rat muscle after death [J]. Journal of Forensic Medicine, 2021,37(01):7-10.
15. Wang, Hanbo, et al. "Methyl jasmonate induces the resistance of postharvest blueberry to gray mold caused by Botrytis cinerea." Journal of the Science of Food and Agriculture 100.11 (2020): 4272-4281.https://doi.org/10.1002/jsfa.10469
16. [IF=3.591] Hengchang Ma et al."Multiple cation-doped linear polymers toward ATP sensing and a cell imaging application."New J Chem. 2018 Jun;42(12):9702-9708
17. [IF=3.772] Y. Duan et al."Antifungal mechanism of Streptomyces ma. FS-4 on fusarium wilt of banana."J Appl Microbiol. 2021 Jan;130(1):196-207
18. [IF=4.36] Yu-fei Li et al."The Chinese medicine babaodan suppresses LPS-induced sepsis by inhibiting NLRP3-mediated inflammasome activation."J Ethnopharmacol. 2022 Jun;292:115205
19. [IF=7.514] Chang Shu et al."Postharvest vibration-induced apple quality deterioration is associated with the energy dissipation system."Food Chem. 2022 Aug;386:132767

ATP,100mM Solution - Nature

Open Data Verified Data
  • This product is white or off-white powder, odorless and odorless, with hygroscopicity. Soluble in water, in ethanol, ether, chloroform or other organic solvents, very slightly soluble.
  • ATP is widely distributed in biological cells, with the highest content in mammalian muscle tissue. It is the central material of the energy storage and release of the organism, and the energy produced by the metabolism of the substance in the body and the energy required for various physiological and biochemical functional activities must be converted by it. The high energy bonds required for the synthesis of GTP and CTP are also transferred from ATP. When the two high energy bonds contained in the ATP molecule are hydrolyzed by the enzyme, each bond can release 54. 24KJ. mol-1 of energy. Exogenous ATP intravenous injection can inhibit myocardial calcium influx, promote potassium outflow, inhibit sinoatrial node automaticity, slow atrioventricular conduction; And can expand local blood vessels, causing transient hypotension.
Last Update：2024-01-02 23:10:35

ATP,100mM Solution - Preparation Method

Open Data Verified Data
  1. rabbit muscle crushing, extraction, barium acetate and mercury nitrate precipitation two times, and then after Mercury and sodium salt.
  2. 5F-adenine nucleotide (5 '-amp) is used as a raw material to produce ATP by providing chloroplasts from spinach for photosynthesis, I .e., photosynthetic phosphorylation.
  3. ATP was obtained from 5r-amp using yeast adenylate kinase, I .e., an oxidative phosphorylation method.
  4. direct fermentation of short ammonia producing bacteria.
Last Update：2022-01-01 11:13:01

ATP,100mM Solution - Standard

Authoritative Data Verified Data

This product is adenine nucleoside -5. Triphosphate disodium salt trihydrate. The content of C10H14N5Na2O11P3 shall not be less than 95.0% calculated as anhydrous.

Last Update：2024-01-02 23:10:35

ATP,100mM Solution - Trait

Authoritative Data Verified Data
  • This product is white or off-white powder or crystalline material; Odorless; With hygroscopicity.
  • This product is soluble in water, almost insoluble in ethanol or ether.
Last Update：2022-01-01 11:30:48

ATP,100mM Solution - Use

Open Data Verified Data

coenzyme. For progressive muscular atrophy, cerebral hemorrhage sequelae, cardiac insufficiency, myocardial disease and hepatitis.

Last Update：2022-01-01 11:13:01

ATP,100mM Solution - Differential diagnosis

Authoritative Data Verified Data
  1. take about 20mg of this product, add 2ml of dilute nitric acid to dissolve, add 1ml of ammonium molybdate test solution, water bath heating, cold, yellow precipitate.
  2. take 3ml of this product aqueous solution (3-10 000), add 0.2ml of 3, 5-dihydroxytoluene ethanol solution (1-10), and add 3ml of ferrous ammonium sulfate hydrochloric acid solution (1 -1000), after heating in a water bath for 10 minutes, the color was green.
  3. The infrared absorption spectrum of this product should be consistent with that of the control (Spectrum set 903).
  4. the product of the aqueous solution of sodium salt identification (1) of the reaction (General 0301).
Last Update：2022-01-01 11:30:48

ATP,100mM Solution - Safety

Open Data Verified Data
  • when used for myocardial infarction and cerebral hemorrhage, the application should be started 2 to 3 weeks after the onset of the disease. Less side effects; Intravenous injection should be slow.
  • Storage, shading, closed, cold preservation.
Last Update：2022-01-01 11:13:01

ATP,100mM Solution - Exam

Authoritative Data Verified Data

acidity

take 0.5g of this product, Add 10ml of water to dissolve, and measure according to law (General rule 0631). The pH value should be 2.5~3.5.

clarity and color of solution

take 0.15g of this product, Add 10ml of water to dissolve, check according to law (General rule 0901 and general rule 0902 method 1), the solution should be clear and colorless; If color, comparison with yellow No. 1 Standard Colorimetric solution should not be deeper.

Related substances

take this product and determine it according to the weight ratio method of adenosine disodium triphosphate under the content determination item.

moisture

take the right amount of this product, precision weighing, with ethylene glycol-anhydrous methanol (60:40) as the solvent, so that the sample is dissolved completely, the moisture content shall be between 0832 and 6.0% as determined by the method for moisture determination (General rule 12.0%, Method 1).

chloride

take 0.10g of this product and check it according to law (General rule 0801). Compared with the control solution made of 0.05% of standard sodium chloride solution, it should not be more concentrated () o

Iron Salt

take l.Og of this product and check it according to law (General rule 0807). Compared with the control solution made of 0.001% of standard iron solution, it shall not be deeper ().

Heavy metals

take l.Og of this product, add 23ml of water to dissolve, add 2ml of acetate buffer (pH 3.5), and check according to law (General rule 0821 first law), containing heavy metals not more than 10 parts per million.

bacterial endotoxin

take this product, check according to law (General rule 1143), each 1 mg adenosine disodium triphosphate containing endotoxin amount should be less than 2.0EU.

Last Update：2022-01-01 11:30:49

ATP,100mM Solution - Content determination

Authoritative Data Verified Data

Total nucleotides

take the right amount of this product, precision weighing, add 0.lmol/L phosphate buffer solution (35.8g of disodium hydrogen phosphate, 13.6 ml of water, g of anhydrous potassium dihydrogen phosphate, and ml of water were added. Dissolve and quantitatively dilute to make a solution containing 20ug per 1 ml and measure the absorbance at a wavelength of 0401 nm by UV-Vis spectrophotometry (general), the absorption coefficient of C10H14N5Na2O11P3 was calculated to be 279. The weight of adenosine disodium triphosphate was determined in comparison with high performance liquid chromatography (General 0512).

chromatographic conditions and system suitability test

silica gel bonded with eighteen alkyl silane as filler; 0.2mol/L phosphate buffer solution (35.8g of disodium hydrogen phosphate, 13.6g of potassium dihydrogen phosphate, of water, adjust pH value to 7.0 with 1 mL/L sodium hydroxide solution, add tetrabutylammonium bromide 1.61g, add water to 1000ml, shake well)-methanol (95:5) as mobile phase; Column temperature was 35°C; the detection wavelength was 259nm. Take 2ml of test solution, heat in water bath for 1 hour, as positioning solution, take 1 u1 with precision, inject human liquid chromatograph, compare with chromatogram of test solution, the order of peak was adenosine monophosphate and adenosine diphosphate. The number of theoretical plates shall not be less than 1500 calculated by adenosine triphosphate peak, and the separation degree between chromatographic peaks shall meet the requirements.

assay

take an appropriate amount of this product, accurately weigh, add mobile phase to dissolve and quantitatively dilute to make a solution containing 0.4mg per lml, inject 10ul into the liquid chromatograph, record the chromatogram, the weight ratio of adenosine disodium triphosphate in total nucleotides was calculated according to the following formula.

Last Update：2022-01-01 11:30:50

ATP,100mM Solution - Category

Authoritative Data Verified Data

cell metabolism improving drugs.

Last Update：2022-01-01 11:30:50

ATP,100mM Solution - Storage

Authoritative Data Verified Data

sealed, cool and dark dry place.

Last Update：2022-01-01 11:30:50
ATP,100mM Solution
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Shanghai Yuanye Bio-Technology Co., Ltd.
Featured ProductsMultiple SpecificationsSpot supply
Product Name: 5'-ATP,Na2 Visit Supplier Webpage Request for quotation
CAS: 987-65-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: Adenosine 5'-triphosphate, disodium salt Request for quotation
CAS: 987-65-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Zouping Mingxing Chemical Co., Ltd.
Product Name: Adenosine 5'-triphosphate disodium salt Request for quotation
CAS: 987-65-5
Tel: 0086-13605431940
Email: xuli678323@126.com
Mobile: +86-13605431940
QQ: 56860987 Click to send a QQ message
Wechat: 13605431940
WhatsApp: 13605431940
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ATP,100mM Solution
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